Human Bone morphogenetic protein 5 (BMP5) ELISA Kit

From Assay Genie, this Sandwich ELISA kit is designed for the quantitative detection of human Bone morphogenetic protein 5 (BMP5; also known as BMP-5) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit uses a colorimetric detection method and is specific for natural and recombinant human BMP5. According to the manufacturer, the detection range is 0.312-20ng/mL with a sensitivity of 0.182ng/mL, while reported precision values are an intra-assay CV of 7.6% and an inter-assay CV of 8.9%. The product is intended for research use only.

BMP5 is a disulfide-linked homodimer belonging to the TGF-beta family that induces cartilage and bone formation. It is secreted to the extracellular space and is involved in skeletal morphogenesis, with dysregulation linked to skeletal disorders, making it a biomarker of interest in bone-related research as well as in orthopedics, regenerative medicine, and musculoskeletal biology. It is also studied in cancer research. The protein is catalogued under UniProt P22003 with a molecular weight of 47,670 Da, and the BMP5 gene (NCBI Gene ID 653) maps to chromosomal location 6p12.1.