Human BLM (Bloom syndrome protein homolog) ELISA KIT (HUFI08238)

Quantitative immunoassay from Assay Genie for measuring Bloom syndrome protein homolog (BLM) concentrations in human-derived research samples. BLM is a RecQ family DNA helicase that safeguards genome stability by processing late-stage homologous recombination intermediates, supporting replication fork recovery, and resolving replication stress. Germline mutations that disable BLM cause Bloom syndrome, an autosomal recessive condition featuring elevated sister chromatid exchange, growth deficiency, and dramatically increased susceptibility to multiple cancer types. Research applications include DNA damage response studies, Fanconi anemia pathway crosstalk, replication fork protection, and tumor biology investigations. The plate-based colorimetric workflow is supplied in a 96 Assays configuration compatible with standard microplate readers, with all critical reagents provided in single-use vials. Unopened components should be stored refrigerated; freeze-thaw cycles of prepared standards should be minimized to preserve calibration integrity. Refer to the enclosed protocol for appropriate dilution of serum-type or plasma-type specimens prior to measurement, and reserve this kit for research use only.