Human Beta-defensin 127 (DEFB127) ELISA Kit

A high-quality sandwich ELISA from Assay Genie designed for the accurate detection of human beta-defensin 127 (DEFB127) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. The kit is reactive with human samples and offers high sensitivity and specificity, delivering reliable and reproducible results for a variety of research applications.

Performance specifications include a detection range of 93.75-6000pg/mL and a sensitivity of 43pg/mL. Intra-assay CV is reported at 4.5% and inter-assay CV at 9.2%. Linearity has been validated in serum, EDTA plasma and heparin plasma across dilutions from 1:2 to 1:16. Recovery averages 99% in serum (range 93-105%) and 101% in plasma (range 95-107%). The assay is specific to natural and recombinant human beta-defensin 127.

Beta-defensin 127 is a secreted antimicrobial peptide of the beta-defensin family, contributing to innate immune defence, skin barrier function and the regulation of inflammation. It exhibits antibacterial function, and elevated levels have been associated with skin disorders, autoimmune diseases and inflammatory conditions, making it a useful biomarker for research. For research use only.