Human Beclin 1 (BECN1) ELISA Kit

Beclin 1 (BECN1) is a key regulator of autophagy, the conserved catabolic pathway responsible for degrading damaged organelles, misfolded proteins, and intracellular pathogens. This quantitative immunoassay from Assay Genie enables researchers to measure Beclin 1 protein concentrations across multiple sample matrices, supporting investigations into tumor biology, neurodegeneration, and cardiovascular disease mechanisms.

The 96-assay kit is validated for use with cell lysates, tissue homogenate preparations, cell culture supernatant samples, and human serum or plasma specimens, accommodating both in vitro cell-based experiments and translational research workflows. Autophagy dysregulation is implicated in cancers of the breast, ovary, and colon, as well as in Alzheimer's disease, Parkinson's disease, and ischemic heart injury, making reliable BECN1 quantification valuable for biomarker discovery and pathway analysis.

Each kit is supplied as a complete package containing the pre-coated microplate, detection antibody, recombinant protein standards, and substrate reagents required to generate a standard curve. Researchers commonly pair this ELISA with western blot validation, PCR-based expression analysis, and cell culture stimulation experiments to confirm autophagy flux changes under pharmaceutical or genetic manipulation.