Human BCO1 (Beta,beta-carotene 15,15?-dioxygenase) ELISA KIT (HUFI05415)

The BCO1 enzyme catalyzes the symmetric cleavage of provitamin A carotenoids, including beta-carotene, to generate retinaldehyde, the immediate precursor of retinol and retinoic acid. This Assay Genie kit enables researchers to quantify circulating levels of this dioxygenase, supporting studies in vitamin A metabolism, carotenoid bioconversion, hepatic retinoid signaling, and nutritional genomics. BCO1 polymorphisms such as A379V (rs7501331) have been linked to inter-individual variation in provitamin A conversion efficiency, making quantitative measurement valuable in population-level nutritional and ophthalmologic research. The microplate format is intended for in vitro research use only and provides reproducible data from human biospecimens. Reagents should be stored refrigerated, with aliquoted standard kept frozen to limit repeated freeze-thaw cycles.