Human Bcl2 Associated X Protein (Bax) ELISA Kit

A quantitative immunoassay from Assay Genie for measuring the pro-apoptotic protein Bax in human research specimens, this ELISA kit supports apoptosis pathway investigations in oncology, neurodegeneration, and toxicology studies. Bax is a 21 kDa member of the Bcl-2 family that translocates to mitochondria and promotes cytochrome c release during programmed cell death.

The assay is configured for microplate-based quantification with all critical reagents supplied in a single kit box sufficient for one full plate run. Researchers profile endogenous Bax across multiple human specimen matrices including serum fractions, plasma samples, tissue homogenate preparations, and cell lysates, with absorbance-based signal readout enabling concentration interpolation against the supplied standard curve.

Typical applications include profiling apoptotic responses to chemotherapeutic agents, monitoring mitochondrial damage in neurodegeneration models, validating Bax expression changes following siRNA or CRISPR-mediated gene knockdown, and characterizing stress-induced cell death in hepatic and cardiac injury models. The kit is calibrated for research use only and is not intended for clinical diagnostic procedures.