Human Bcl-2-binding component 3 (BBC3) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA kit is designed for the quantitative detection of human Bcl-2-binding component 3 (BBC3) in human samples. The target protein, also known by the synonyms JFY-1, p53 up-regulated modulator of apoptosis, and PUMA (UniProt Q9BXH1), is a BH3-only pro-apoptotic member of the BCL-2 family that functions as an essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis and is localised to the mitochondria.

The kit is intended for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and is supplied for cancer research applications. According to the manufacturer, the assay has a detection range of 0.156-10ng/mL and a sensitivity of 0.09ng/mL, with specificity for natural and recombinant human Bcl-2-binding component 3, isoforms 1/2. The product is for research use only.