Human BCKDK ([3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial) ELISA KIT (HUFI05501)

The Assay Genie immunoassay kit enables quantitative measurement of human BCKDK, the mitochondrial kinase that phosphorylates and inactivates the branched-chain α-ketoacid dehydrogenase complex. By modulating branched-chain amino acid catabolism, BCKDK sits at a regulatory node connecting BCAA homeostasis to mTOR signaling, insulin response, and neuronal excitability. Researchers studying metabolic syndrome, type 2 diabetes, and obesity-related pathways use BCKDK quantification to track how dietary or pharmacological interventions shift tissue kinase activity. In oncology, elevated BCKDK expression has been reported in several solid tumor types, where it can support tumor growth by suppressing BCAA oxidation; the kit supports biomarker validation in cell culture models and tissue extracts. Neuroscience laboratories investigating maple syrup urine disease and related BCAA catabolism defects profile BCKDK levels to characterize variant effects and screen candidate therapeutics. The kit is supplied as a pack of 96 Assays and is intended for research use only, with all reagents validated for in vitro measurement workflows.