Human Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2) ELISA Kit

This Sandwich ELISA kit from Assay Genie uses colorimetric detection for the precise measurement of human basement membrane-specific heparan sulfate proteoglycan core protein (HSPG2), also known as perlecan (synonyms PLC, HSPG). The assay detects both natural and recombinant forms of HSPG2 with high specificity, supporting research into cell adhesion, migration, and signaling. Dysregulation of HSPG2 has been linked to cancer, diabetes, and cardiovascular disorders, highlighting its significance as a potential biomarker for disease progression and therapeutic development.

The kit is validated for human samples including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Key performance characteristics include a detection range of 0.625-40ng/mL and a sensitivity of 0.31ng/mL, with intra-assay CV of 4.3% and inter-assay CV of 7.1%.

Linearity has been demonstrated across dilutions from 1:2 to 1:16 in serum (88-117%), EDTA plasma (86-120%), and heparin plasma (83-115%). Recovery ranges from 91-103% in serum and 93-105% in plasma. For research use only.