Human BAG1 ELISA Kit (HUFI04618)

BAG1 (BCL2-associated athanogene 1) is a multifunctional cochaperone that modulates Hsp70 chaperone activity and influences apoptosis regulation through BCL-2 family interactions. This Assay Genie kit provides a quantitative immunoassay for measuring human BAG1 protein in laboratory samples, supporting investigations into cancer cell survival, stress response, and chaperone-mediated signaling pathways. The kit format includes all reagents needed to perform 96 Assays using a standard microplate workflow, making it practical for screening cohorts in oncology biomarker research. BAG1 occurs as several isoforms—BAG-1L localized predominantly in the nucleus, BAG-1M in the cytoplasm, and the shorter BAG-1S form—each contributing differently to nuclear receptor regulation, transcription factor activity, and proteasomal targeting of client proteins. Published studies link altered BAG1 expression to breast, colorectal, prostate, and lung cancer prognosis, where it is often examined alongside other apoptotic regulators. Store reagents refrigerated; equilibrate plates to room temperature before initiating the assay protocol.