Human B7-H2/ICOS Ligand PharmaGenie ELISA Kit (SBRS0292)

B7-H2 (also known as ICOS Ligand, ICOSL, B7h, B7RP-1, GL50, and CD275) is a type I transmembrane glycoprotein belonging to the B7 family of immune co-stimulatory molecules. It binds ICOS on activated T cells and contributes to T-cell proliferation, cytokine secretion, and germinal center formation. Constitutive expression is found on B cells, macrophages, and dendritic cells, and the ligand can be upregulated on non-lymphoid cells by inflammatory stimuli such as TNF-alpha and LPS. Assay Genie's B7-H2/ICOS Ligand PharmaGenie ELISA Kit is a quantitative immunoassay for measuring this target in human cell culture supernatants, plasma, and serum samples. The kit is supplied as a 96-assay plate and produces a colorimetric readout compatible with standard microplate readers in immunology and cell biology laboratories. Researchers investigating co-stimulatory signaling, autoimmune disease, transplant tolerance, asthma, and the tumor microenvironment can profile ICOSL expression under varied experimental conditions with this reagent. Each kit includes a pre-coated plate, detection antibody, standards, and reagents necessary to run the full assay, and the components are intended for research use only.