Human B2M PharmaGenie ELISA Kit (SBRS0289)

This quantitative immunoassay from Assay Genie measures human beta-2-microglobulin (B2M), a small ~11.8 kDa invariant chain that anchors MHC class I molecules on the cell surface. Researchers rely on this kit to investigate immune regulation, HLA class I turnover, renal tubular function, and biomarkers in lymphoproliferative and plasma cell disorders.

The assay accepts cell culture supernatants, plasma, and serum, supporting translational workflows that bridge in vitro cell models with patient-derived material. Each kit supplies a pre-coated microplate and reagents calibrated for 96 determinations, with absorbance-based signal generation at the end of the run. Reagents should be stored refrigerated and protected from light to preserve activity through the stated shelf life.

Beta-2-microglobulin quantification carries clinical relevance for monitoring kidney filtration, evaluating dialysis adequacy, and characterizing multiple myeloma and lymphoma, where elevated B2M levels correlate with tumor burden and prognosis. The Assay Genie format enables reproducible measurement of this low-molecular-weight protein across diverse experimental conditions.