Human B-lymphocyte antigen CD19 (CD19) ELISA Kit

CD19 is a 95 kDa transmembrane glycoprotein of the immunoglobulin superfamily that defines the B-lymphocyte lineage from the pro-B cell stage through mature B-cell development, and this Assay Genie ELISA Kit enables quantitative measurement of this biomarker in human research specimens.

As a co-receptor alongside CD21 and CD81 in B-cell receptor signaling, CD19 is a focal analyte in studies of humoral immunity, autoimmune disease mechanisms, and B-cell malignancies including chronic lymphocytic leukemia and non-Hodgkin lymphoma.

This microplate-based kit is configured for 96 assays and includes a pre-coated plate, biotin-conjugated detection antibody, streptavidin-HRP conjugate, wash buffer, substrate solution, stop solution, and recombinant CD19 standards. The assay is intended for in vitro research use only with human serum or plasma specimens.

Storage recommendations call for refrigerated handling of unopened kit components; allow all reagents to reach room temperature before use, and avoid repeated freeze-thaw cycles of standard and sample preparations.

Common applications include biomarker screening in immunology and hematology research, evaluation of B-cell involvement in autoimmune conditions such as systemic lupus erythematosus and rheumatoid arthritis, and longitudinal monitoring of CD19 expression in clinical research cohorts investigating CAR-T cell therapy outcomes and minimal residual disease.