Human B-cell CLL/lymphoma 6 member B protein (BCL6B) ELISA Kit

Designed for the precise quantification of human B-cell CLL/lymphoma 6 member B protein (BCL6B), this Sandwich ELISA Kit from Assay Genie supports research into B-cell development, lymphoma and leukemia pathogenesis, and biomarker discovery in hematological malignancies.

The assay is intended for human samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and detects both natural and recombinant BCL6B. Reported performance figures include a detection range of 0.78-50ng/mL, a sensitivity of 0.34ng/ml, an intra-assay CV of 4.6% and an inter-assay CV of 8.3%. Recovery is given as 98% (range 92-104%) in serum and 100% (range 94-106%) in plasma, with linearity spanning 83-120% across serum, EDTA plasma and heparin plasma at dilutions of 1:2 to 1:16.

BCL6B (UniProt Q8N143) is a sequence-specific transcriptional repressor that associates with BCL6 through the BTB domain and localises to the nucleus. It is a C2H2-type zinc finger transcription factor with a reported molecular weight of 51,531 Da, encoded at chromosomal location 17p13.1. Synonyms include BAZF, ZNF62 and ZBTB28, and the relevant research area is epigenetics. For research use only.