Human Axl PharmaGenie ELISA Kit (SBRS0287)

Axl is a member of the TAM receptor tyrosine kinase family (Tyro3, Axl, MerTK), a group of single-pass transmembrane receptors that bind the ligands Gas6 and Protein S to regulate innate immune cell clearance, inflammatory signaling, and cell survival. Aberrant Axl expression is documented across multiple solid tumors and hematologic malignancies, where it contributes to epithelial-to-mesenchymal transition, therapy resistance, and metastatic dissemination, making it a marker of interest in oncology, immunology, and cell signaling research.

The Assay Genie Human Axl PharmaGenie ELISA Kit is configured as a 96-assay microplate immunoassay built around matched capture and detection antibody pairs directed against the extracellular domain of human Axl. The assay produces a colorimetric signal quantified on a standard plate reader, with a workflow that handles conditioned media from cultured cells and blood-derived matrices from human donors. Each kit is supplied as a single-use reagent pack with a pre-coated plate, intended for in vitro research use only in laboratory settings studying TAM receptor biology, tumor invasion, immune regulation, and biomarker discovery.