Human ATP Binding Cassette Transporter A3 (ABCA3) ELISA Kit

Researchers studying pulmonary surfactant biology, neonatal respiratory distress, or hereditary interstitial lung disease can use the Assay Genie Human ABCA3 ELISA Kit to quantify ATP Binding Cassette Transporter A3 in human tissue homogenates. ABCA3 is a lipid transporter highly expressed in alveolar type II pneumocytes, where it loads phosphatidylcholine into lamellar bodies for surfactant assembly; loss-of-function mutations in the gene are linked to neonatal respiratory failure and pediatric interstitial lung disease.

The kit delivers a colorimetric readout from a matched antibody pair immobilized on the plate, with signal intensity proportional to ABCA3 concentration. Reagents for 96 assays ship in a single pack, and the procedure accommodates lysates prepared from lung biopsies and select cell culture models. Reconstituted standards and diluted samples are handled at room temperature during the run, while kit components are stored refrigerated between uses to preserve activity. All reagents are for research use only and are not intended for clinical diagnostic procedures.