Human ATP-binding cassette sub-family G member 2 (ABCG2) ELISA Kit

A Sandwich ELISA from Assay Genie designed for the quantitative measurement of human ATP-binding cassette sub-family G member 2 (ABCG2) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. ABCG2 is a vital transporter protein with roles in drug resistance and protection against xenobiotics, and its expression is associated with cancer, neurological disorders and cardiovascular conditions, making it a valuable biomarker for research into these disorders.

The kit reports a detection range of 0.156-10ng/mL and a sensitivity of 0.067ng/mL. Precision is given as an Intra CV of 3.8% and an Inter CV of 7.2%. Linearity has been assessed across dilutions of 1:2, 1:4, 1:8 and 1:16 for serum (N=5), EDTA plasma (N=5) and heparin plasma (N=5), with recovery reported as an average of 107% (101-113%) for serum and 109% (103-115%) for plasma. Specificity is established against natural and recombinant human ATP-binding cassette sub-family G member 2, and the research area is listed as Neurosciences.

Synonyms referenced for the target include Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, Urate exporter, CD338, ABCP, BCRP, BCRP1 and MXR. The associated UniProt entry is Q9UNQ0. For research use only.