Human ATP-binding cassette sub-family A member 7 (ABCA7) ELISA Kit

This Sandwich ELISA Kit from Assay Genie is designed for the precise measurement of human ATP-binding cassette sub-family A member 7 (ABCA7) levels in research specimens. ABCA7 is a member of the ATP-binding cassette transporter family that plays a role in cellular lipid transport, lipid homeostasis, and macrophage-mediated phagocytosis. Dysregulation of ABCA7 has been linked to Alzheimer's disease, atherosclerosis, and other neurodegenerative disorders, making it a valuable biomarker for studying these conditions and developing potential diagnostic and treatment strategies.

The kit uses a colorimetric detection method with a detection range of 0.156-10 ng/ml and a sensitivity of 0.045 ng/ml. Reported precision values are 3.2% intra-assay CV and 7.4% inter-assay CV. Recovery in serum averaged 100% (range 94-106%) and in plasma averaged 102% (range 96-108%). Acceptable sample types include serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. The kit recognises both natural and recombinant human Phospholipid-transporting ATPase ABCA7 (UniProt Q8IZY2). Synonyms listed for the target include ABCA-SSN, ATP-binding cassette sub-family A member 7, Autoantigen SS-N, and Macrophage ABC transporter. The research area is Cell Biology.

For research use only.