Human Ataxin 1 (ATXN1) ELISA Kit

Ataxin-1 (ATXN1) is a DNA-binding transcriptional regulator whose abnormal CAG-repeat expansion drives Spinocerebellar ataxia type 1 (SCA1), a progressive neurodegenerative disorder affecting cerebellar Purkinje cells. This quantitative ELISA kit from Assay Genie provides researchers with a reliable microplate-based assay to quantify Ataxin-1 protein in human research specimens, supporting investigations into polyglutamine protein aggregation, mutant allele expression, and the Ataxin-1/Capicua transcriptional repressor complex.

The workflow pairs capture and detection antibodies directed against immunodominant epitopes of the human protein, and the resulting chromogenic signal is read on a standard spectrophotometer. Pre-coated plate strips, lyophilized standards, and detection reagents are packaged in a single kit sized for 96 determinations, enabling mid-throughput screening of patient samples, transfected cell lines, and iPSC-derived neuronal disease models.

Reagents are stable when stored refrigerated according to the included protocol, and the assay is intended for research use only in studies of SCA1 pathogenesis, biomarker discovery, and therapeutic development.