Human ASF1A ELISA Kit (HUFI04619)

The Assay Genie ELISA Kit provides quantitative measurement of human ASF1A (Anti-Silencing Function 1A Histone Chaperone), an H3/H4 histone chaperone that delivers histones to chromatin-assembly machinery and supports replication-coupled nucleosome deposition. The kit supports research into ASF1A's role in DNA damage response, cell-cycle progression, and transcriptional regulation, areas of active investigation in cancer biology and chromatin studies.

Configured for in vitro research use, the kit accommodates studies of circulating ASF1A levels in clinical cohorts, profiling of histone chaperone expression in tumor-derived cell lines, and mechanistic work on chromatin assembly factors. Published literature links ASF1A activity to histone supply during S-phase, maintenance of heterochromatin boundaries, and cooperation with CAF-1 and MCM complexes; the assay complements ChIP-seq, Western blotting, and qPCR workflows that characterize chromatin states.

Supplied as a microplate-format package containing pre-coated wells, detection reagents, and standard curve material sufficient for one full plate run, the kit is paired with standard sample collection protocols for blood-derived fractions. Abundance data from the immunoassay can be correlated with patient outcomes, treatment response, or genetic status of upstream regulators such as TLK kinases and HIRA.