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Human Arylsulfatase B/ARSB PharmaGenie ELISA Kit (SBRS0281)
  • Human Arylsulfatase B/ARSB PharmaGenie ELISA Kit (SBRS0281)
Assay Genie

Human Arylsulfatase B/ARSB PharmaGenie ELISA Kit (SBRS0281)

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SBRS0281

Price on request

Description

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Built for quantitative measurement of human arylsulfatase B (ARSB), this Assay Genie ELISA Kit supports research into lysosomal storage disorders, in particular Mucopolysaccharidosis VI (Maroteaux-Lamy syndrome), where loss of ARSB activity leads to accumulation of dermatan sulfate. ARSB, also called N-acetylgalactosamine-4-sulfatase, is a lysosomal enzyme that removes the 4-sulfate group from N-acetylgalactosamine residues during glycosaminoglycan catabolism. The kit is for research use only and has been validated for quantifying ARSB in plasma, serum, and cell culture supernatant. It is supplied as a 96-assay kit with a pre-coated microplate, recombinant ARSB standards, a matched detection antibody, substrate solution, wash buffer, and assay diluent needed to build a standard curve. Workflows follow standard in vitro immunoassay practice, and the kit fits translational and biomarker studies aimed at enzyme replacement, GAG metabolism, and rare-disease biology.