Human ARHGDIB (Rho GDP-dissociation inhibitor 2) ELISA Kit (HUFI04628)

The Assay Genie Human ARHGDIB ELISA Kit enables quantitative measurement of Rho GDP-dissociation inhibitor 2 (RhoGDI2), a cytosolic modulator of Rho family GTPase signaling. ARHGDIB governs the cytoplasmic-membrane cycling of RhoA, Rac1, and Cdc42, processes central to cell adhesion, motility, and cytoskeletal reorganization. Investigators in oncology, immunology, and cell biology deploy this assay to explore RhoGDI2 expression in tumor invasion models, leukocyte chemotaxis, and inflammatory signaling cascades where dysregulated Rho GTPase activity is implicated.

Built on a 96 Assays microplate with absorbance-based readout, the kit supplies a pre-coated plate, biotinylated detection reagent, standard calibrators, and assay buffers sufficient to evaluate multiple sample concentrations in duplicate wells per run. Reagents remain stable under refrigerated storage, and the protocol accommodates common human liquid specimens collected for clinical or translational biomarker studies.

Applications include RhoGDI2 quantification in research contexts such as bladder carcinoma progression, ovarian tumor microenvironment analysis, and T-cell activation assays. The kit is intended for research use only and is not validated for diagnostic purposes.