Human Argininosuccinate Synthetase 1 (ASS1) ELISA Kit

This human-targeted immunoassay kit from Assay Genie enables quantitative measurement of Argininosuccinate Synthetase 1 (ASS1), a cytosolic enzyme that catalyzes the ATP-dependent ligation of citrulline and aspartate to form argininosuccinate within the hepatic urea cycle. The 96-assay kit is intended for research use only and supports studies into inherited urea cycle disorders such as citrullinemia type I, hepatocellular injury, and ASS1 silencing observed across solid tumors including melanoma, renal cell carcinoma, and prostate cancer.

Assay Genie's colorimetric ELISA serves translational oncology workflows where loss of ASS1 expression marks metabolic vulnerability and arginine auxotrophy in tumors. Investigators profiling hepatic tissue, plasma fractions, and tumor lysates can track ASS1 levels in patient cohorts and in vitro cell models subjected to arginine depletion or pharmacologic stress on the urea cycle.

Configured in a 96-assay plate layout, the kit accommodates parallel measurement of experimental and control conditions across multiple biological replicates, making it a practical addition to biomarker discovery pipelines in human metabolic and cancer research.