Human Arginase II (Arg2) ELISA Kit

Quantitative measurement of endogenous human Arginase II in research specimens is the focus of the Assay Genie Arg2 immunoassay kit. The mitochondrial isoenzyme Arg2 hydrolyzes L-arginine to ornithine and urea, positioning it at a key branch point between the urea cycle, polyamine synthesis, and nitric oxide production. Aberrant Arg2 expression has been linked to endothelial dysfunction, hepatocellular injury, tumor proliferation, and altered macrophage phenotypes in published studies.

The kit accommodates multiple human specimen matrices, including tissue homogenates, cell lysates, cell culture supernatants, and blood-derived fractions. This range supports both in vitro cell-based experiments and translational research using clinical samples. Investigators examining arginine pathway remodeling in cardiovascular disease, immune polarization in inflammatory models, or metabolic dysregulation in cancer biology can apply Arg2 quantification across their experimental workflows.

Each kit is supplied in a 96 assays format with sufficient microplate wells for standard curves, internal controls, and experimental replicates. Readout uses an absorbance-based method compatible with standard laboratory microplate readers, requiring no specialized instrumentation. The kit is intended for research use only and is not validated for diagnostic or clinical decision-making.