Human Aquaporin 4 (AQP4) ELISA Kit

Aquaporin 4 (AQP4) is a water-selective membrane channel protein critical for maintaining water homeostasis in the central nervous system. Research-grade quantification of AQP4 in clinical and experimental samples requires a robust, reproducible immunoassay, and this Assay Genie ELISA Kit provides a quantitative tool for measuring human AQP4 protein levels. The kit is supplied in a 96 assays configuration suitable for moderately sized studies.

AQP4 expression is of particular interest in studies of neuromyelitis optica spectrum disorder (NMOSD), where autoantibodies target the protein, and the kit supports investigation of this and related neurological conditions. The assay is configured for use with human serum samples, plasma samples, and tissue homogenates, giving flexibility across multiple specimen sources from human subjects. Researchers studying kidney, brain, and respiratory tissue can apply the kit to compare AQP4 concentrations across healthy and diseased states.

The procedure uses a colorimetric readout, allowing quantitation on a standard microplate reader. Each kit provides the essential components to process a standard lab microplate in established workflows. Storage is straightforward: keep the kit refrigerated and protect from light until use to maintain reagent activity. The assay is intended for research use only and is not cleared for diagnostic procedures.