Human Aquaporin-3 (AQP3) ELISA Kit

From Assay Genie, this ELISA kit is designed for the quantitative measurement of human Aquaporin-3 (AQP3) in serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It is reactive with human samples and is intended for research use only. The kit detects natural and recombinant human Aquaporin-3, also known by the synonyms Aquaglyceroporin-3 and AQP-3, using a colorimetric detection method.

According to the manufacturer datasheet, the assay has a detection range of 0.156–10 ng/mL and a sensitivity of 0.072 ng/mL. Reported precision values are an intra-assay CV of 4.1% and an inter-assay CV of 7.9%. Spiked recovery is stated for serum (average 97%, range 91–103%) and plasma (average 99%, range 93–105%), with linearity percentages provided across 1:2 to 1:16 dilutions for serum, EDTA plasma and heparin plasma. Aquaporin-3 (UniProt Q92482) is described as a water channel protein that promotes glycerol permeability and water transport across cell membranes, with roles in skin hydration, wound healing, renal water homeostasis and tumorigenesis. It localises to the basolateral cell membrane in the collecting ducts of the kidney.