Human Apoptosis Signal Regulating Kinase 1 (ASK1) ELISA Kit

Stress-activated kinase signaling through ASK1, encoded by the MAP3K5 gene, links cytokine receptor engagement, oxidative challenge, and endoplasmic reticulum stress to downstream JNK and p38 MAPK cascade activation. Dysregulation of this mitogen-activated protein kinase kinase kinase contributes to cardiac hypertrophy, neurodegeneration, inflammatory disease, and tumor progression, making quantitative protein measurement valuable in translational research programs.

From Assay Genie, this ELISA kit enables quantification of human ASK1 protein in cell lysate and tissue homogenate preparations. The assay uses a microplate format compatible with standard laboratory plate readers, with kit reagents supplied in quantities sufficient for 96 assays in a single experimental run. Investigators studying apoptosis regulation, TNF-alpha signal transduction, or cellular stress response biology can apply this kit to compare ASK1 abundance across treated and untreated cohorts.

Each kit contains pre-coated plate wells, diluents, wash buffers, and detection components for benchtop immunodetection workflows. The product is intended for research use only and serves academic and pharmaceutical laboratories running apoptosis and kinase pathway studies.