Human APEX2 (DNA- (apurinic or apyrimidinic site)lyase 2) ELISA KIT (HUFI08246)

APEX2 (apurinic/apyrimidinic endonuclease 2) is a key component of the cellular base excision repair (BER) pathway, where it cleaves the phosphodiester backbone immediately 5' of abasic sites generated by spontaneous hydrolysis, deamination, or oxidative damage, and where it also processes 3'-blocking termini at DNA strand breaks. It has become a research focus in cancer biology, neurodegeneration, and DNA damage response studies, particularly in the context of genotoxic stress, chemoresistance, and tumor-microenvironment investigations. This Assay Genie kit provides a quantitative immunoassay for human APEX2, with all reagents required for the procedure included in a microplate-based workflow and a chromogenic endpoint read on a standard laboratory plate reader. Designed for research use only, the assay supports measurement of APEX2 in cellular models of genotoxic stress, comparisons between tumor and adjacent tissue samples, and patient-cohort studies of BER pathway biomarkers. Components are shipped cold-packed and should be stored refrigerated until first use, with reconstituted standards and detection antibody aliquoted and kept on ice for short-term handling.