Human AP-2 complex subunit beta (AP2B1) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the accurate quantification of human AP-2 complex subunit beta (AP2B1) levels in human samples including serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. The kit offers high sensitivity and specificity for natural and recombinant human AP2B1, with a detection range of 0.312–20 ng/mL and a sensitivity of 0.11 ng/mL.

Performance characteristics include an intra-assay CV of 5.6% and an inter-assay CV of 9.2%. Linearity has been evaluated in serum, EDTA plasma, and heparin plasma across multiple dilutions, with serum recovery averaging 97% (range 91–103%) and plasma recovery averaging 99% (range 93–105%).

AP2B1 is a key component of the AP-2 adaptor complex, which plays a critical role in clathrin-mediated endocytosis and intracellular trafficking. Dysregulation of AP2B1 has been linked to various diseases, including cancer, neurodegenerative disorders, and infectious diseases, making this kit a valuable tool for researchers in neurosciences studying endocytic pathways and disease mechanisms. For research use only.