Human AP-1 ELISA Kit

This Sandwich ELISA from Assay Genie is designed for the quantitative measurement of AP-1 (Activator Protein 1) in human samples. The kit employs a double antibody format with colorimetric detection using a TMB substrate, with absorbance read at 450 nm, and is intended for research in Epigenetics and Nuclear Signaling.

Validated sample types include serum, plasma, cell or tissue lysate, and other liquid samples. Recovery is 89–98% in serum (average 93%), 89–104% in EDTA plasma (average 97%), and 86–98% in heparin plasma (average 92%). Dilutional linearity across 1:2, 1:4 and 1:8 dilutions falls within 82–102% in serum, 84–103% in EDTA plasma, and 81–104% in heparin plasma. Kit reagents are stored at 2–8°C for 12 months.

AP-1 is a transcription factor complex that regulates gene expression and influences processes including cell proliferation, differentiation and apoptosis. Its dysregulation has been implicated in cancer, inflammatory disorders and neurodegenerative conditions, making it a relevant target for studies of disease mechanisms and therapeutic strategies.