Human ANGPTL3 PharmaGenie ELISA Kit (SBRS0257)

Angiopoietin-like protein 3 (ANGPTL3) is a hepatocyte-derived secreted factor that regulates plasma triglyceride and high-density lipoprotein cholesterol by inhibiting lipoprotein lipase and endothelial lipase activity, positioning it as a central biomarker in cardiovascular and metabolic disease research. This quantitative immunoassay from Assay Genie quantifies human ANGPTL3 across multiple sample matrices including conditioned media from cultured cells, plasma, and serum, supporting translational studies into dyslipidemia, atherosclerosis, non-alcoholic fatty liver disease, and the mechanisms of investigational lipid-lowering agents that target the angiopoietin-like protein pathway. Reagents are supplied for 96 assays and the kit is intended for in vitro research use only, enabling clinical sample profiling, patient cohort stratification by lipid phenotype, and characterization of ANGPTL3 loss-of-function mutations linked to familial combined hypolipidemia. Reconstituted standards and working antibody solutions should be handled according to the enclosed protocol; unopened components are refrigerated and protected from light to preserve binding activity and standard curve integrity across repeated freeze-thaw cycles of prepared reagents.