Human and Mouse Phospho-LSD1 (S112) PharmaGenie ELISA Kit (SBRS1883)

This Phospho-LSD1 (S112) ELISA from Assay Genie quantifies lysine-specific demethylase 1A (KDM1A) when phosphorylated at serine 112, a regulatory modification that influences LSD1's association with the CoREST repressor complex and its H3K4 demethylase function within chromatin remodeling pathways.

Used in cell signaling, epigenetics, and oncology research, the kit measures phospho-LSD1 in cell lysates and tissue lysates from human and mouse samples, with demonstrated cross-reactivity toward mouse LSD1. This makes it useful for translational studies in xenograft tissues and genetically modified mouse models where S112 phosphorylation is being tracked alongside downstream histone methylation changes.

Supplied as a 96-assay microplate kit with colorimetric readout, reagents should be stored at 4 degrees C and equilibrated to room temperature before running the assay. Recommended applications include kinase pathway profiling, small-molecule inhibitor screening, and characterization of post-translational regulation of LSD1 in cancer cell lines and stem cell models.