Human Amelogenin,X-Linked (AMELX) ELISA Kit

Targeting the X-linked isoform of human amelogenin, this immunoassay kit from Assay Genie quantifies AMELX protein in tissue homogenates and laboratory samples. AMELX is one of the most abundant proteins secreted by ameloblasts during enamel mineralization, and mutations in the AMELX gene on chromosome Xp22.2 are directly linked to X-linked amelogenesis imperfecta, a hereditary condition that disrupts normal enamel structure. By targeting the X-linked isoform specifically, this kit differs from AMELY-directed assays and supports studies that require separation of sex-chromosome-derived amelogenin contributions, including forensic odontology applications, dental pulp tissue analysis, and developmental biology research.

Cell culture studies of ameloblast and odontoblast lines, biomarker investigations in mineralized tissue research, and characterization of hereditary enamel defects are typical use cases. The kit is supplied in a 96 assays configuration suited to medium-throughput workflows, and the protocol is validated for reactivity with human samples in research laboratories studying oral biology, dental science, and craniofacial development.