Human Alpha-crystallin B chain (CRYAB) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA Kit enables quantitative measurement of human Alpha-crystallin B chain (CRYAB). Reactive with human samples, it supports detection of CRYAB, a small heat shock protein implicated in cellular stress response, neurodegenerative disorders, cardiovascular diseases, and inflammatory conditions.

Performance characteristics include a detection range of 0.156-10ng/mL, a sensitivity of 0.089ng/mL, an intra-assay CV of 4.9%, and an inter-assay CV of 7.8%. The kit is specific for natural and recombinant human Alpha-crystallin B chain. Recovery is 100% (94-106%) for serum and 102% (96-108%) for plasma.

CRYAB, with synonyms including Alpha(B)-crystallin, Heat shock protein beta-5 (HspB5), HSPB5, CRYA2, Renal carcinoma antigen NY-REN-27, and Rosenthal fiber component (UniProt P02511), contributes to lens transparency and refractive index, and exhibits chaperone-like activity that prevents aggregation of various proteins under a wide range of stress conditions. Compatible samples include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The kit is for research use only and falls within the Cancer research area.