Human ALK tyrosine kinase receptor (ALK) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the precise and accurate detection of Human ALK (Anaplastic Lymphoma Kinase, CD246) Tyrosine Kinase Receptor levels. The kit is reactive with Human samples, including serum, plasma, tissue homogenates, cell culture supernates and other biological fluids, and uses a colorimetric ELISA detection method.

Key performance characteristics include a detection range of 0.312-20ng/mL and a sensitivity of 0.12ng/mL. Intra-assay CV is 3.2% and inter-assay CV is 6.3%. Recovery is reported as 88% (82-94%) for serum and 90% (84-96%) for plasma. The kit is specific for natural and recombinant human ALK tyrosine kinase receptor and is intended for the Signal Transduction research area. It is for research use only.

ALK is a receptor tyrosine kinase that plays a crucial role in cell growth, proliferation, and survival. Mutations or dysregulation of ALK have been implicated in various cancers, including anaplastic large cell lymphoma and non-small cell lung cancer, making it a valuable biomarker for studying these diseases and developing targeted therapies.