Human ALK-6/BMPR-IB PharmaGenie ELISA Kit (SBRS0246)

Quantify activin receptor-like kinase 6, the bone morphogenetic protein receptor type 1B (BMPR1B), in human samples using this solid-phase immunoassay from Assay Genie. The 96-determination format supports signaling pathway research on bone formation, chondrogenesis, and reproductive biology, where BMPR1B activity modulates SMAD-dependent transcription downstream of BMP2, BMP4, BMP6, BMP7, and GDF5 ligands.

The kit accommodates cell culture supernatants alongside clinical sample matrices, enabling studies that compare receptor expression across primary osteoblasts, chondrocytes, granulosa cells, and patient-derived isolates. Researchers investigating brachydactyly type A2 and related skeletal dysplasias, as well as ovarian folliculogenesis, rely on isoform-specific measurement to distinguish BMPR1B from the closely related BMPR1A receptor.

Components include pre-coated microplate wells, matched detection antibody, and substrate solution for chromogenic readout on a standard plate reader. All reagents are intended for research use only, supporting laboratory workflows that examine BMP pathway dysregulation in cancer, fibrosis, and metabolic bone disease.