Human ALK-1 PharmaGenie ELISA Kit (SBRS0245)

Human ALK-1, also known as ACVRL1, is a type I receptor of the TGF-β superfamily expressed predominantly on vascular endothelial cells. It plays a central role in angiogenesis and vascular remodelling, with mutations linked to hereditary hemorrhagic telangiectasia type 2 (HHT2) and pulmonary arterial hypertension.

Researchers use this Assay Genie ELISA kit to quantify circulating ALK-1 concentrations in human samples including plasma, serum, and cell culture supernatant for studies of endothelial signalling, cardiovascular disease mechanisms, and therapeutic target validation. The kit provides a pre-coated microplate, biotinylated detection antibody, calibrated standards, and substrate solution.