Human Aldosterone Synthase (ALDOS) ELISA Kit

Aldosterone synthase (ALDOS), the cytochrome P450 enzyme encoded by the CYP11B2 gene, performs the final hydroxylation and oxidation reactions that convert 11-deoxycorticosterone to aldosterone within mitochondria of the zona glomerulosa in the human adrenal cortex. This Assay Genie quantitative immunoassay measures ALDOS protein levels, supporting investigation of primary aldosteronism, secondary hypertension, congestive heart failure, adrenal adenoma pathophysiology, and renin-angiotensin-aldosterone system (RAAS) dysregulation.

The microplate-based kit is calibrated to detect ALDOS across multiple human sample matrices, including individual serum fractions, matched plasma aliquots, and zona glomerulosa tissue homogenates. Researchers characterizing steroidogenesis, electrolyte balance, mineralocorticoid receptor signaling, and cardiovascular remodeling will find the assay useful for biomarker quantification in translational and basic science workflows. Reagents are shipped refrigerated; protect from light and avoid repeated freeze-thaw cycles to preserve reagent activity. The product is intended for research use only and is not validated for diagnostic procedures.