Human ALDH1A1 PharmaGenie ELISA Kit (SBRS0243)

ALDH1A1 (Aldehyde Dehydrogenase 1 Family Member A1) is a cytosolic enzyme that catalyzes the oxidation of retinaldehyde to retinoic acid, a signaling molecule central to embryogenesis, hematopoiesis, and tissue homeostasis. Elevated ALDH1A1 activity has been linked to cancer stem cell populations, chemoresistance, and tumor aggressiveness in lung, breast, ovarian, and colorectal cancers, positioning the protein as a biomarker of interest in preclinical and translational research.

The Human ALDH1A1 PharmaGenie ELISA Kit, distributed under the Assay Genie brand, uses paired antibody capture with a colorimetric endpoint to quantify human ALDH1A1 protein across plasma, serum, and conditioned media from cultured cells. The kit is intended for research use only, supporting in vitro workflows. Typical applications include profiling ALDH1A1 expression in stem cell populations, retinoid pathway studies, and investigation of chemotherapy resistance mechanisms in solid tumor models.

Provided as a complete kit with pre-coated microplate wells, the reagents support up to 96 assays. The colorimetric method relies on absorbance measurement at a single wavelength, integrating cleanly with standard plate-reader workflows. Researchers studying acute myeloid leukemia, glioblastoma stem-like cells, or hepatocellular carcinoma use this ELISA to correlate ALDH1A1 levels with stemness markers and drug response phenotypes.