Human AKAP12/A Kinase Anchor Protein 12 ELISA Kit

From Assay Genie, this is a Sandwich ELISA, Double Antibody kit designed for the quantitative measurement of human AKAP12 (A Kinase Anchor Protein 12), also known as Gravin, in human biological samples including serum, plasma, cell culture supernatant, cell or tissue lysate, and other liquid samples. The assay uses colorimetric detection and operates with a sensitivity of 9.375 pg/mL across a measuring range of 15.625-1000 pg/mL.

AKAP12 functions as a scaffold for signalling molecules, regulating cellular processes such as cell communication, migration, and proliferation. Dysregulation of AKAP12 has been implicated in cancer, cardiovascular disorders, and neurological conditions, making it a relevant biomarker for disease research and therapeutic development. Reported validation includes linearity across 1:2, 1:4, and 1:8 dilutions in serum (92-99%, 86-99%, 85-101%), EDTA plasma (86-99%, 84-98%, 89-105%), and heparin plasma (86-99%, 82-90%, 87-100%), with sample recovery averages of 97% in serum, EDTA plasma, and heparin plasma. The associated Uniprot entry is Q02952, and reagents are stored at 2-8°C for 12 months.