Human AIF PharmaGenie ELISA Kit (SBRS0240)

AIF executes its lethal program by translocating from the mitochondrial intermembrane space to the nucleus, where it drives caspase-independent chromatinolysis (parthanatos), a pathway now implicated in ischemic stroke, traumatic brain injury, Parkinson's disease, and chemotherapy regimens that evade classical caspase-driven apoptosis. Assay Genie supplies the kit in a 96 assays microplate configuration calibrated against recombinant AIFM1 reference material, supporting consistent lot-to-lot recovery for longitudinal studies. Because capture antibodies recognize only human epitopes and show no significant cross-reactivity with mouse or rat AIFM1 homologs, rodent-focused laboratories should pair this kit with an orthologous assay. Reconstituted standards should be aliquoted and stored at -20 °C, and the unopened kit remains stable refrigerated at 4 °C; both conditions are also printed on the product insert.