Human Advanced glycosylation end product-specific receptor (AGER) ELISA Kit

Assay Genie offers a sandwich-format ELISA for the quantitative detection of human Advanced Glycosylation End Product-Specific Receptor (AGER), also known as Receptor for Advanced Glycosylation End Products (RAGE). Using a colorimetric detection method, the kit is reactive with human samples and is intended for research use only.

The assay delivers a detection range of 31.2-2000pg/mL and a sensitivity of 15.7pg/mL. Reported precision includes an intra-assay CV of 6.3% and an inter-assay CV of 8.6%. The kit is specific for natural and recombinant human AGER and supports research applications in neurosciences.

Validated sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. AGER is a member of the immunoglobulin superfamily of cell surface receptors that mediates interactions with advanced glycosylation end products (AGEs). Dysregulation of AGER has been linked to diabetes, atherosclerosis, Alzheimer's disease, and inflammation-related conditions, making the receptor a target of interest for studies of disease mechanisms and therapeutic development. The associated UniProt accession is Q15109.