Human Adenosine receptor A1 (ADORA1) ELISA Kit

The product is a Sandwich ELISA Kit from Assay Genie designed for the precise measurement of human Adenosine receptor A1 (ADORA1) levels in samples including serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The colorimetric assay has a detection range of 0.156–10 ng/mL and a sensitivity of 0.056 ng/mL.

Performance characteristics include an Intra-assay CV of 5.9% and Inter-assay CV of 8.3%. Recovery has been validated in serum (average 86%, range 80–92%) and plasma (average 88%, range 82–94%), and linearity has been assessed across serial dilutions of serum, EDTA plasma, and heparin plasma. The kit is specific for both natural and recombinant human ADORA1.

ADORA1 is a G-protein coupled receptor for adenosine whose activity is mediated by G proteins that inhibit adenylyl cyclase. The receptor is involved in neurotransmission, inflammation, and immune response, and its dysregulation has been linked to Parkinson's disease, epilepsy, and inflammatory disorders, making it a valuable target for cardiovascular research and broader therapeutic investigation. The product is intended for research use only.