Human ACVR2A (Activin receptor type-2A) ELISA KIT (HUFI05478)

Activin A Receptor Type 2A (ACVR2A) is a type II receptor of the TGF-beta superfamily that mediates signaling for activin A, myostatin, and several bone morphogenetic proteins. Because ACVR2A mutations recur in microsatellite-unstable colorectal tumors, and because circulating receptor fragments are of interest in reproductive endocrinology and muscle-wasting research, quantitative measurement of human ACVR2A in research samples supports multiple lines of investigation.

This Assay Genie kit provides the reagents and a microplate configured for 96 individual determinations for quantifying human ACVR2A in research specimens. The workflow uses a biotin-streptavidin-HRP detection approach with a colorimetric endpoint read on a standard plate reader after substrate addition and stop reagent. Standard curves are generated from the included calibrators, and unknown concentrations are interpolated from the curve using the recommended dilution. Researchers can apply serum-type specimens, plasma-type specimens, or related cleared matrices collected under an approved study protocol.

Kit components include a pre-coated plate, calibrators, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer concentrate, substrate solution, and stop solution. Unopened components are stored refrigerated; reconstituted reagents follow the stability guidance printed in the manual. The kit is supplied in a single-use format for research use only and is not validated for diagnostic or therapeutic decision-making.