Human Actinin Alpha 2 (ACTN2) ELISA Kit

The Assay Genie ACTN2 ELISA Kit targets alpha-actinin 2, a Z-disc protein essential for sarcomere organization in cardiac and skeletal muscle. The kit is relevant for research on hypertrophic cardiomyopathy, dilated cardiomyopathy, and skeletal muscle myopathies linked to ACTN2 mutations. The microplate-based format uses a 100 uL sample volume per well of tissue homogenate, with the human-specific capture antibody providing specificity without significant cross-reactivity with rat or mouse orthologs. Researchers investigating mechanotransduction, Z-disc signaling, and cytoskeletal remodeling will find this assay useful for quantitative protein level analysis in cell and tissue lysates.