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Human ACMSD (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase) ELISA KIT (HUFI08247)
  • Human ACMSD (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase) ELISA KIT (HUFI08247)
Assay Genie

Human ACMSD (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase) ELISA KIT (HUFI08247)

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HUFI08247

Price on request

Description

This description has not been verified against the manufacturer's datasheet. Check the datasheet before you order, or ask us to confirm a specification. Ask us to confirm

The ACMSD enzyme (2-amino-3-carboxymuconate-6-semialdehyde decarboxylase) occupies a pivotal branch point in the kynurenine pathway of tryptophan catabolism, directing flux away from the neurotoxic intermediate quinolinic acid and toward 2-aminomuconate-6-semialdehyde. Because this step also feeds NAD+ biosynthesis, quantitative measurement of ACMSD protein in human biospecimens supports research into renal injury, neurodegeneration, and inflammatory disease mechanisms.

This Assay Genie ELISA kit is configured for research use only and provides a microplate-based immunoassay workflow with colorimetric readout on a standard plate reader. The kit includes pre-coated wells, standards, and detection reagents sufficient for running standard curves alongside unknown specimens in a single plate.

Storage and handling: refrigerate the kit upon receipt and protect reagents from light. Allow all components to equilibrate to room temperature before beginning the assay. Consult the enclosed protocol for full reagent preparation, assay procedure, and data analysis guidance.