Human ABCC5/ATP Binding Cassette Transporter C5 ELISA Kit

Assay Genie provides a Sandwich ELISA Kit designed for the quantitative detection of human ABCC5 (ATP Binding Cassette Transporter C5). This colorimetric immunoassay is intended for research applications and offers high sensitivity and specificity for measuring ABCC5 levels in human samples. ABCC5 is an important transporter protein involved in drug resistance and cellular detoxification, and its expression and function have been linked to various diseases including cancer, cystic fibrosis, and cardiovascular disorders.

The kit is reactive with human samples and validated for serum, plasma, cell culture supernatant, cell or tissue lysates, and other liquid samples. It delivers a sensitivity of 46.875 pg/mL with a working range of 78.125–5000 pg/mL and uses a double-antibody sandwich format. Storage is at 2–8°C for up to 12 months. Performance has been characterised across serum, EDTA plasma, and heparin plasma, with linearity of 90–102%, 84–105%, and 82–100% respectively at 1:2, 1:4, and 1:8 dilutions, and average recoveries of 96–98%.

ABCC5 is a member of the ATP-binding cassette transporter family and is relevant to research in signal transduction and disease pathology. The kit supports investigations into ABCC5 function and regulation, aiding studies of drug resistance mechanisms, cellular detoxification, and potential therapeutic strategies in health and disease.