Human ABCB11 (Bile salt export pump) ELISA KIT (HUFI08241)

The ABCB11 protein, also known as the bile salt export pump (BSEP), is a hepatocyte canalicular membrane transporter essential for biliary bile acid excretion. Research applications include studies of progressive familial intrahepatic cholestasis type 2, drug-induced cholestasis, and hepatic transporter pharmacology. This Assay Genie reagent employs human-specific capture antibodies, enabling quantitative measurement in patient serum-type specimens without significant cross-reactivity with related ABC transporters. The detection range covers a broad span appropriate for both healthy baseline samples and elevated cholestatic patient values. Store unopened kit components at -20°C, allow the microplate to equilibrate to room temperature before use, and protect the TMB substrate from light. Reconstitute the lyophilized standard in the provided diluent for accurate quantification, and aliquot unused reconstituted standard to limit freeze-thaw cycles.