Human 5-Hydroxytryptamine Receptor 2B (HTR2B) ELISA Kit

The HTR2B gene encodes a seven-transmembrane G protein-coupled receptor that mediates serotonin signaling through Gq-mediated phospholipase C activation and intracellular calcium mobilization. This Assay Genie kit enables quantitative measurement of receptor levels in human serum-based samples, EDTA-plasma preparations, and tissue homogenate preparations. Researchers investigating cardiac valvulopathy, pulmonary vascular remodeling, or serotonergic neuron function can use the microplate-based protocol to track receptor abundance across experimental cohorts. Reconstituted standards and detection antibodies remain stable when aliquoted and stored at -20°C; bring all components to room temperature before pipetting. Each run includes a standard curve of recombinant HTR2B antigen for interpolating unknown sample concentrations, with results reported in ng/mL.