Human 4-1BB Ligand PharmaGenie ELISA Kit (SBRS0210)

Researchers investigating T cell co-stimulation, cancer immunotherapy, and autoimmune disease can quantitatively measure soluble 4-1BB Ligand (TNFSF9) using the PharmaGenie ELISA Kit from Assay Genie. The assay is validated across three sample matrices — cell culture supernatant, blood plasma, and serum — making it suitable for diverse immunology, oncology, and cell biology workflows.

4-1BB Ligand is a type II transmembrane glycoprotein of the tumor necrosis factor superfamily that engages the co-stimulatory receptor 4-1BB (CD137) on activated T cells. Engagement of this axis amplifies T cell proliferation, drives IL-2 and IFN-γ production, supports CD8+ memory T cell formation, and is a focus of next-generation cancer immunotherapy research. The ligand is also studied in the context of autoimmune disease, transplant tolerance, and chronic inflammatory disorders.

Each kit provides reagents for 96 assays in a microplate-based format with a chromogenic enzymatic readout, intended for research use only. Reagents should be stored refrigerated between uses to preserve stability, and the assay has been validated specifically for detection of human 4-1BB Ligand.